Background: Non-alcoholic fatty liver disease (NAFLD) has increased over the past years. NAFLD occurs when liver cells begin to collect fat droplets. Liver enzymes are the best indicator for assessing liver status. Incidence of this disease in women is higher than men, although opposite results have been reported. NAFLD patients have unhealthy lifestyle in both diet and physical activity. In the present study, the effect of mental and muscle relaxation in water was investigated to evaluate changes in liver enzymes and inflammatory markers (IL-6 and C-reactive protein (CRP) of NAFLD patients.
Methods: The present study was a randomized clinical trial with pretest-posttest and follow-up with control group. Liver enzymes and inflammatory markers include IL-6 and CRP were measured before and after mental and muscle relaxation in water. Finally, the data analysis was made with independent samples t-test for baseline variables in two groups, paired t-test and two-way mixed ANOVA (repeated measures) used for measuring indices in pretest and posttest of within group and between groups respectively. Also, the correlation test was used to evaluate the correlation between age and FBS with liver enzymes.
Results: We found significant reductions in measured indices (FBS, AST, ALT, ALP, IL-6, and CRP), within the treatment group in comparison with the control group (P < 0.05). Also, there were significant differences in means of AST (P < 0.001), ALT (P = 0.002), ALP (P=0.021), IL-6 (P < 0.001), and CRP (P = 0.019) between two groups after mental and muscle relaxation in water.
Conclusion: our results demonstrated that mental and muscle relaxation in the water had a significant role in improving and reducing the symptoms of NAFLD patients.