Aims: Considering that in the last decade, obesity in children has been increasing significantly and obesity is directly related to high blood pressure, we decided to examine the status of blood pressure in terms of body mass index in children under 9 years. Instrument & Methods: This descriptive cross-sectional study was conducted during 2017-18 in Tabriz University of Medical Sciences with the participation of 1000 under 9-year-old children. Children were included in the study based on inclusion and exclusion criteria and their body mass index and blood pressure were measured and their blood pressure status was assessed based on body mass index classification. Findings: The mean total systolic blood pressure of the study participants was 101.49±6.18 and the mean total diastolic blood pressure of the study participants was 65.19±4.12. With increasing body mass index, blood pressure was significantly increased. Conclusion: The higher the body mass index of children, the higher the systolic and diastolic blood pressure.
S.a. Hoseinikhah, S. Pazooki, H. Jarineshin, F. Fekrat, Volume 4, Issue 3 (7-2025)
Abstract
Aims: Spinal anesthesia-induced hypotension is a major challenge during cesarean sections under spinal anesthesia. Ondansetron may be a good option for solving this complication. This study aimed to evaluate the effect of ondansetron in preventing spinal anesthesia-induced hypotension in pregnant women undergoing elective cesarean section. Materials & Methods: This prospective clinical trial was conducted in 2023 with 120 pregnant women classified as ASA I or II. The women were divided into two groups: One group received 4mg of ondansetron diluted in 10ml saline, and the second group received 10ml of normal saline. Different parameters, including systolic and diastolic blood pressure, heart rate, and SpO2, were recorded at multiple time intervals. The incidence of nausea, vomiting, and shivering was also assessed. Findings:The ondansetron group showed a significant reduction in systolic and diastolic blood pressure compared to the saline group at several intervals immediately following the block. The results did not show differences in heart rate between the two groups, except during recovery, when the normal saline group had a higher heart rate. The incidence of nausea and shivering was similar between groups, while vomiting was slightly less frequent in the ondansetron group; the difference was not statistically significant. Conclusion:Ondansetron may temporarily reduce blood pressure following spinal anesthesia in pregnant women undergoing cesarean section. Further studies are needed to determine its role in preventing hypotension during spinal anesthesia and to explore its potential effects on other perioperative parameters.
