Volume 1, Issue 4 (2022)                   GMJM 2022, 1(4): 149-152 | Back to browse issues page
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Noei Alamdary S, Ghasembaglou S. Relationship of Serum Vitamin D levels with Tonsillar and Adenoid Hypertrophy in Children. GMJM 2022; 1 (4) :149-152
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1- Department of Otorhinolaryngology, School of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran
* Corresponding Author Address: Department of Otorhinolaryngology, School of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran. (shahramgasembaglou@yahoo.com)
Abstract   (520 Views)
Aims: Vitamin D has also been shown to reduce respiratory infections in children. The aim of this study was to investigate the relationship between serum vitamin D levels and tonsillar and adenoid hypertrophy in children.
Instrument & Methods: This study was a retrospective cross-sectional study that was performed on 140 children with symptoms of tonsillitis referred to the hospitals of Tabriz University of Medical Sciences. All patients were divided into four groups according to the degree of tonsillitis and their severity of tonsillitis was compared with the serum level of vitamin D.
Findings: Children were divided into four groups based on their grade level. There was no statistically significant difference in terms of gender between the four groups (p=0.845). The average level of vitamin D in children is as follows: Grade 1: Vitamin D level was 18.12±2.27 ng/dL; Grade 2 had vitamin D levels of 17.48±2.54 ng/dL; Grade 3 had vitamin D levels of 15.27±2.03 ng/dl, and grade 4 children had vitamin D levels of 15.01±2.12 ng/dL. Comparison of vitamin D levels in different groups was not statistically significant (p=0.557).
Conclusion: There is no relationship between vitamin D levels and clinical signs and symptoms of tonsillitis in children.
 
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References
1. Dogru M, Evcimik MF, Calim OF. Does adenoid hypertrophy affect disease severity in children with allergic rhinitis?. Eur Arch Otorhinolaryngol. 2017;274:209-13. [Link] [DOI:10.1007/s00405-016-4196-x]
2. Hussain M, Borcard L, Walsh KP, Pena Rodriguez M, Mueller C, Kim BS, et al. J Allergy Clin Immunol. 2018;141(1):223--234.e5. [Link] [DOI:10.1016/j.jaci.2017.02.035]
3. Li J, Mei X, Cai X, Zhuo Y, Zhang L, Guo H, et al. Association of blood eosinophilia and vitamin D insufficiency in young infants with cow milk allergy. Asia Pac J Clin Nutr. 2019;28(3):550-7. [Link]
4. Smith CJ, Kluck LA, Ruan GJ, Ashrani AA, Hook CC, Marshall AL. The differential diagnosis of basophilia in patients undergoing BCR-ABL testing. Am J Hematol., 2020;95(9):E216-E217. [Link] [DOI:10.1002/ajh.25830]
5. Ekici NY, Görgülü O, Yucel G, Külahci O,. Arikan OK, Durmaz C. Can the number of eosinophils in adenoid and tonsil tissue determine the allergy in children?. Int J Pediatr Otorhinolaryngol. 2018;108:35-9. [Link] [DOI:10.1016/j.ijporl.2018.02.008]
6. Pereira L, Monyror J, Almeida FT, Almeida FR, Guerra E, Flores-Mir C, et al. Prevalence of adenoid hypertrophy: A systematic review and meta-analysis. Sleep Med Rev. 2018;38:101-12. [Link] [DOI:10.1016/j.smrv.2017.06.001]
7. Mandle HB, Jahan FA, Bostick RM, Baron JA, Barry EL, Yacoub R, et al. Effects of supplemental calcium and vitamin D on tight-junction proteins and mucin-12 expression in the normal rectal mucosa of colorectal adenoma patients. Mol Carcinogen. 2019;58(7):1279-90. [Link] [DOI:10.1002/mc.23010]
8. Chen H, Lu R, Zhang YG, Sun J. Vitamin D receptor deletion leads to the destruction of tight and adherens junctions in lungs. Tissue Barriers. 2018;6(4):1-13. [Link] [DOI:10.1080/21688370.2018.1540904]
9. Martineau AR, Jolliffe DA, Hooper RL, Greenberg L, Aloia JF, Bergman P, et al. Vitamin D supplementation to prevent acute respiratory tract infections: systematic review and meta-analysis of individual participant data. BMJ. 2017;356:i6583. [Link] [DOI:10.1136/bmj.i6583]
10. Aglipay M, Birken CS, Parkin PC, Loeb MB, Thorpe K, Chen Y, et al. JAMA. 2017;318:245-54. [Link] [DOI:10.1001/jama.2017.8708]
11. Kaufman HW, Niles JK, Kroll MH, Bi C, Holick HF. SARS-CoV-2 positivity rates associated with circulating 25-hydroxyvitamin D levels. PLoS One. 2020;15:e0239252. [Link] [DOI:10.1371/journal.pone.0239252]
12. Jimenez-Sousa MA, Martinez I, Medrano LM, Fernandez-Rodriguez A, Resino S. Vitamin D in human immunodeficiency virus infection: Influence on immunity and disease. Front Immunol. 2018;9:458. [] [DOI:10.3389/fimmu.2018.00458]
13. Radujkovic A, Hippchen T, Tiwari-Heckler S, Dreher S, Boxberger M, Merle U. Vitamin D deficiency and outcome of COVID-19 patients. Nutrients, 2020;12(9):2757. [Link] [DOI:10.3390/nu12092757]
14. Griffin G, Hewison M, Hopkin J, Kenny R, Quinton R, Rhodes J, et al. R Soc Open Sci. 2020;7(12):201912. [Link] [DOI:10.1098/rsos.201912]
15. Meckel K, Li YC, Lim J, Kocherginsky M, Weber C, Almoghrabi A, et al. Serum 25-hydroxyvitamin D concentration is inversely associated with mucosal inflammation in patients with ulcerative colitis. Am J Clin Nutr. 2016;104(1):113-20. [Link] [DOI:10.3945/ajcn.115.123786]
16. Liang G, Conrad MA, Kelsen JR, Kessler LR, Breton J, Albenberg LG, et al. Dynamics of the stool virome in very early-onset inflammatory bowel disease. J Crohns Colitis. 2020;14(11):1600-10. [Link] [DOI:10.1093/ecco-jcc/jjaa094]
17. Banerjee A, De P, Manna B, Chawla-Sarkar M. Molecular characterization of enteric adenovirus genotypes 40 and 41 identified in children with acute gastroenteritis in Kolkata, India during 2013-2014. J Med Virol. 2017;89(4):606-14. [Link] [DOI:10.1002/jmv.24672]
18. Silva LG, Ferguson BS, Avila AS, Faciola AP. Sodium propionate and sodium butyrate effects on histone deacetylase (HDAC) activity, histone acetylation, and inflammatory gene expression in bovine mammary epithelial cells. J Anim Sci. 2018;96(12):5244-52. [Link] [DOI:10.1093/jas/sky373]
19. Chen C, Niu M, Pan J, Du N, Liu S, Li H, et al. Gut Pathog. 2021;13(1):1. [Link] [DOI:10.1186/s13099-020-00395-0]
20. Lynch III JP, Kajon AE. Adenovirus: Epidemiology, global spread of novel serotypes, and advances in treatment and prevention. Semin Respir Crit Care Med. 2016;37(4):586-602. [Link] [DOI:10.1055/s-0036-1584923]